News

Integration Multi-Omics analysis - Workshop and Symposium

29-08-2017

Organized by: Renee Menezes (VUmc) and Perry Moerland (AMC)

Omics technology has revolutionized molecular approaches towards understanding (human) disease. Unfortunately, data stemming from various omics platforms, such as genomics, transcriptomics and proteomics, tend to be analyzed separately. To fully harness the power of these big data, a simultaneous analysis is required. This two-day event aims to bring up and discuss the latest methodology for doing so.

The symposium on state-of-the-art methods for integrated multi-omics analysis will take place on November the 24th 2017 at the AMC, room Coster/Fonteynzaal G0-209. It will be preceded by a workshop on November the 23rd on front-line methods to explore multi-omics data, and we will have a guest speaker on both days, Florian Markowetz. The description and preliminary program for each day is:


Workshop (23rd November)

For researchers interested in learning front-line methods to explore multi-omics data. This will involve two sessions:

Session 1: Weighted Gene Co-expression Analysis (WGCNA) & (Sparse) canonical correlation analysis, by Koos Zwinderman (AMC) and Perry Moerland (AMC)


Session 2: Methods for network reconstruction using omics data, by Wessel van Wieringen (VU/VUmc) and Carel Peeters (VUmc)

Each session will involve a lecture followed by a hands-on session, during which participants will get a better feel for the methods by practising on their own laptops. Both sessions will be based in R (http://www.r-project.org). At the end of the day, Florian Markowetz (Cancer Research UK) will give a talk on Reproducible Research. For more information on the content, please contact the organizers via integrationxl@gmail.com .


Symposium (24th November)

Here we will have talks and discussions on various approaches to quantitative multi-omics data analysis, from a wide variety of viewpoints. During the lunch break we will have a poster session, where researchers are encouraged to display their work.  The program will include the following speakers:

  • Renee Menezes (VUmc), on whole-genome methods to find effects of molecular changes on gene expression using multi-omics data
  • Lodewyk Wessels (NKI and TU-Delft), on his take on transfer learning in a multi-omics context
  • Koos Zwinderman (AMC), on sparse canonical correlation analysis and sparse redundancy analysis, and their application on various multi-omics data cohorts
  • Michel Nivard (VU): Integration of brain-omics data and psychiatric trait genome-wide association studies: Tissue matters, summary data often beats raw data, sufficient statistics are king
  • Keynote speaker: Florian Markowetz (Cancer Research UK)


More details about the program will be added in due course. The day will close with drinks.

There are limited places for both of these full-day events, so register soon to guarantee a place, if you haven't done so yet. For registration , please send an email to integrationxl@gmail.com, stating for which day(s) you would like to register: either "Symposium Integration XL" on November 24th, or "Workshop Integration XL" on November 23rd,  or both.

Information about how to get to the AMC can be found here.


Please feel free to share this announcement with people who might be interested, both in the symposium as well as in the workshop.